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Multidrug resistance reversal activity of permethyl ningalin B amide derivatives |
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| Authors: | Tao Houchao Hwang Inkyu Boger Dale L |
| Affiliation: | Department of Chemistry and the Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA |
| Abstract: | A series of amide derivatives of permethyl ningalin B were prepared and examined as multidrug resistance (MDR) reversal agents illustrating that the C5 carboxylate is widely tolerant of such derivatization. |
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