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Tachykinin receptors in the rat brain bind alpha-bungarotoxin |
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| Authors: | Iu N Utkin E M Lazakovich I E Kasheverov S F Arkhipova V I Tsetlin |
| Abstract: | alpha-Bungarotoxin was found to inhibit effectively the binding of 125I-labelled substance P and eledoisin to membrane and to solubilize preparations of the rat brain. Other postsynaptic neurotoxins exerted similar but less pronounced influence on the interaction of tachykinins with their receptors. The obtained results suggest that some alpha-bungarotoxin-binding polypeptides in brain are components of tachykinin receptors. |
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