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Effect of prazosin on human prostatic adenoma tissue |
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| Authors: | M E Kaminka M L Zhirnikova A Z Vinarov M D Mashkovski? Iu A Pytel' |
| Abstract: | The effect of prazosin on epinephrine-induced contractions of human benign prostatic hyperplasia strips was studied. It was shown that prazosin has a pronounced adrenoblocking activity (EC50 = 5.10(-9) g/ml) but fails to affect strip contractions induced by KCL. It is suggested that prazosin can be used in the treatment of patients suffering from benign prostatic hyperplasia. |
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