The preventive influence of cysteamine on the teratogenic action of 5-azacytidine. |
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| Authors: | I K Takeuchi U Murakami |
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| Institution: | Department of Embryology, Institute for Developmental Research, Aichi Prefectural Colony, Kasugai, Aichi 480-03, Japan |
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| Abstract: | The radioprotective agent cysteamine can prevent the teratogenic action of 5-azacytidine in rat fetuses. The preventive influence of cysteamine was observed when applied to the mother not only 3 hours and 30 minutes before the 5-azacytidine administration, but also 30 minutes after it. However, the application of cysteamine 3 hours after the administration of 5-azacytidine showed no preventive influence. |
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