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Erythrocyte oxidative damage by myeloperoxidase. The protective action of serum proteins
Authors:N Iu Govorova  B P Sharonov  S N Lyzlova
Abstract:Influence of main serum proteins (albumin, immunoglobulin G) and proteins-antioxidants (ceruloplasmin, transferrin, superoxide dismutase) on the oxidative damage of erythrocytes by myeloperoxidase and hypochlorite was investigated. The proteins were determined to act as protectors and decrease the degree of hemoglobin oxidation, ceruloplasmin and albumin possessing the highest antioxidant activity.
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