Genome sequencing and functional characterization of the non-pathogenic Klebsiella pneumoniae KpGe bacteria |
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Authors: | Wanessa C. Lima Trestan Pillonel Claire Bertelli Estelle Ifrid Gilbert Greub Pierre Cosson |
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Affiliation: | 1. Cell Physiology and Metabolism Dpt, Faculty of Medicine, University of Geneva, 1 rue Michel Servet, CH-1211, Geneva 4, Switzerland;2. Institute of Microbiology, University of Lausanne and University Hospital Center, 48 rue du Bugnon, CH-1011, Lausanne, Switzerland |
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Abstract: | Klebsiella pneumoniae is an extensively studied human pathogen responsible for a wide variety of infections. Dictyostelium discoideum is a model host organism employed to study many facets of the complex interactions between phagocytic cells and bacteria. Historically, a non-pathogenic strain of K. pneumoniae has been used to feed Dictyostelium amoebae, and more recently to study cellular mechanisms involved in bacterial recognition, ingestion and killing. Here we provide the full genome sequence and functional characterization of this non-pathogenic KpGe strain. |
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Keywords: | Host–pathogen interactions Non-pathogenic strain |
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