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NMR assignments of the binary hvDHFR1:folate complex
Authors:Arezue F. B. Boroujerdi  Bulent Binbuga  John K. Young
Affiliation:(1) Department of Chemistry, Mississippi State University, Box 9573, Mississippi State, MS 39762, USA
Abstract:A better understanding of how salt affects enzyme activity can be gained via NMR studies of binary hvDHFR1:folate complex. Chemical shift assignments of the 17.9 kDa enzyme with bound substrate prepare the way for ongoing research of the effects of salt on enzyme flexibility through relaxation studies.
Keywords:Haloferax volcanii   Dihydrofolate reductase  NMR  Salt  Chemical shift assignments
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