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纳米中药龙胆草复方制剂对实验性大鼠癫痫的防治作用
引用本文:施中凯,胡晓丽,邸智勇,杨景云. 纳米中药龙胆草复方制剂对实验性大鼠癫痫的防治作用[J]. 中国微生态学杂志, 2007, 19(1): 14-15
作者姓名:施中凯  胡晓丽  邸智勇  杨景云
作者单位:1. 黑龙江省医院香坊总院,实验诊断部,黑龙江,哈尔滨,150036
2. 佳木斯大学基础医学院,微生物教研室
摘    要:目的观察纳米中药龙胆草复方制剂扶植肠道双歧杆菌对实验性大鼠癫痫的治疗作用。方法实验以大鼠腹腔注射青霉素600万U/kg制成癫痫模型。应用纳米治疗,检测双歧杆菌及脑内r氨-基丁酸含量的变化。结果纳米中药持续7 d治疗后,肠道双歧杆菌菌量明显上升,与自然恢复组比较差异有极显著性(P<0.01)。脑内r氨-基丁酸含量接近正常。结论纳米中药龙胆草复方制剂具有良好的抗癫痫作用。

关 键 词:癫痫  纳米中药  双歧杆菌
文章编号:1005-376X(2007)01-0014-02
收稿时间:2006-09-20
修稿时间:2006-09-20

To study the Nano-TCML as the complex bolus Long Dan Cao curing the epilepsy rats by injecting the bifidobacterium
SHI Zhong-kai,HU Xiao-li,DI Zhi-yong,YANG Jing-yun. To study the Nano-TCML as the complex bolus Long Dan Cao curing the epilepsy rats by injecting the bifidobacterium[J]. Chinese Journal of Microecology, 2007, 19(1): 14-15
Authors:SHI Zhong-kai  HU Xiao-li  DI Zhi-yong  YANG Jing-yun
Abstract:This study was to make the epilepsy mode by injecting penicllin into the belly of the rat,then adjust the intestinal micro dysbiosis and to cure the rats who contracted the epilepsy.We could detect the changes of the quantity of Bifidobacterium and GABA,to observe the Nano-TCML as the complex bolus of Long Dan Cao,that could cure the epilepsy by adjusting the intestinal micro dysbiosis.After seven days curing,amount of Bifidobacterium obviously raised,all the data were significantly different between the Nano-TCML group and the nomal control group,at the same time,GABA in the brain were neared to the nomal.
Keywords:Epilepsy  Nano-TCML  Bifidobacterium
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