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Herpesvirus DNA in Peripheral Blood Mononuclear Cells of Some Patients with Meniere's Disease
Authors:Kazuo Takahashi  Toshiya Aono  Mitsuo Shichinohe  Manabu Tamura  Yasuhide Iwata  Koichi Yamanishi  Shiro Shigeta
Abstract:Herpes simplex virus‐1 (HSV) or varicella zoster virus (VZV) DNA was detected by nested polymerase chain reaction in peripheral blood mononuclear cells of patients with Meniere's disease (one of 28 patients for HSV‐1,2 of 28 patients for VZV) during acute illness (within 5 days after onset). On the other hand, neither HSV‐1 DNA or VZV DNA was detected in PBMCs of 50 age‐ and sex‐matched healthy individuals and 50 pregnant women. These findings may imply that reactivation of HSV‐1 or VZV may be associated with the development of some cases of Meniere's disease.
Keywords:herpes simplex virus‐1  varicells‐zoster virus  meniere's disease  PCR
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