Characterization of the AGR2 Interactome Uncovers New Players of Protein Disulfide Isomerase Network in Cancer Cells
Authors: Pavla Bouchalova Lucia Sommerova David Potesil Andrea Martisova Petr Lapcik Veronika Koci Alex Scherl Petr Vonka Joan Planas-Iglesias Eric Chevet Pavel Bouchal Roman Hrstka
Affiliation: 1. Department of Biochemistry, Faculty of Science, Masaryk University, Brno, Czech Republic;2. Regional Centre for Applied Molecular Oncology, Masaryk Memorial Cancer Institute, Brno, Czech Republic;3. Central European Institute for Technology, Masaryk University, Brno, Czech Republic;4. National Centre for Biomolecular Research, Faculty of Science, Masaryk University, Brno, Czech Republic;5. Department of Human Protein Sciences, Faculty of Medicine, University of Geneva, Geneva, Switzerland;6. Loschmidt Laboratories, Department of Experimental Biology and RECETOX, Faculty of Science, Masaryk University, Brno, Czech Republic;7. International Clinical Research Center, St Anne''s University Hospital Brno, Brno, Czech Republic;8. INSERM U1242, “Chemistry, Oncogenesis, Stress, Signaling”, Université Rennes 1, Rennes, France
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Keywords: anterior gradient protein 2 protein–protein interactions protein disulfide isomerase mass spectrometry secretory pathway Ab" },{" #name" :" keyword" ," $" :{" id" :" kwrd0040" }," $$" :[{" #name" :" text" ," _" :" antibody ADT3" },{" #name" :" keyword" ," $" :{" id" :" kwrd0050" }," $$" :[{" #name" :" text" ," _" :" arogenate dehydratase 3 AGR2" },{" #name" :" keyword" ," $" :{" id" :" kwrd0060" }," $$" :[{" #name" :" text" ," _" :" anterior gradient 2 BiP" },{" #name" :" keyword" ," $" :{" id" :" kwrd0070" }," $$" :[{" #name" :" text" ," _" :" binding immunoglobulin protein CAM" },{" #name" :" keyword" ," $" :{" id" :" kwrd0080" }," $$" :[{" #name" :" text" ," _" :" carbamidomethyl DMSO" },{" #name" :" keyword" ," $" :{" id" :" kwrd0090" }," $$" :[{" #name" :" text" ," _" :" dimethyl sulfoxide DSP" },{" #name" :" keyword" ," $" :{" id" :" kwrd0100" }," $$" :[{" #name" :" text" ," _" :" dithiobis[succinimidylpropionate] ENPL" },{" #name" :" keyword" ," $" :{" id" :" kwrd0110" }," $$" :[{" #name" :" text" ," _" :" endoplasmin ER" },{" #name" :" keyword" ," $" :{" id" :" kwrd0120" }," $$" :[{" #name" :" text" ," _" :" endoplasmic reticulum FA" },{" #name" :" keyword" ," $" :{" id" :" kwrd0130" }," $$" :[{" #name" :" text" ," _" :" formic acid FDR" },{" #name" :" keyword" ," $" :{" id" :" kwrd0140" }," $$" :[{" #name" :" text" ," _" :" false discovery rate FLNB" },{" #name" :" keyword" ," $" :{" id" :" kwrd0150" }," $$" :[{" #name" :" text" ," _" :" filamin-B GLU2B" },{" #name" :" keyword" ," $" :{" id" :" kwrd0160" }," $$" :[{" #name" :" text" ," _" :" glucosidase 2 subunit beta GO" },{" #name" :" keyword" ," $" :{" id" :" kwrd0170" }," $$" :[{" #name" :" text" ," _" :" Gene Ontology GRP78" },{" #name" :" keyword" ," $" :{" id" :" kwrd0180" }," $$" :[{" #name" :" text" ," _" :" glucose-regulated protein, 78 kDa GSEA" },{" #name" :" keyword" ," $" :{" id" :" kwrd0190" }," $$" :[{" #name" :" text" ," _" :" gene set enrichment analysis HNRPU" },{" #name" :" keyword" ," $" :{" id" :" kwrd0200" }," $$" :[{" #name" :" text" ," _" :" heterogeneous nuclear ribonucleoprotein U HSPA5" },{" #name" :" keyword" ," $" :{" id" :" kwrd0210" }," $$" :[{" #name" :" text" ," _" :" heat shock 70 kDa protein 5 IP" },{" #name" :" keyword" ," $" :{" id" :" kwrd0220" }," $$" :[{" #name" :" text" ," _" :" immunoprecipitation IT" },{" #name" :" keyword" ," $" :{" id" :" kwrd0230" }," $$" :[{" #name" :" text" ," _" :" ion trap LFQ" },{" #name" :" keyword" ," $" :{" id" :" kwrd0240" }," $$" :[{" #name" :" text" ," _" :" label-free quantification log2FC" },{" #name" :" keyword" ," $" :{" id" :" kwrd0250" }," $$" :[{" #name" :" text" ," _" :" log2 fold change LTQ" },{" #name" :" keyword" ," $" :{" id" :" kwrd0260" }," $$" :[{" #name" :" text" ," _" :" linear trap quadrupole MS" },{" #name" :" keyword" ," $" :{" id" :" kwrd0270" }," $$" :[{" #name" :" text" ," _" :" mass spectrometry NC" },{" #name" :" keyword" ," $" :{" id" :" kwrd0280" }," $$" :[{" #name" :" text" ," _" :" negative control NP-40" },{" #name" :" keyword" ," $" :{" id" :" kwrd0290" }," $$" :[{" #name" :" text" ," _" :" Nonidet P-40 OT" },{" #name" :" keyword" ," $" :{" id" :" kwrd0300" }," $$" :[{" #name" :" text" ," _" :" Orbitrap PBS-T" },{" #name" :" keyword" ," $" :{" id" :" kwrd0310" }," $$" :[{" #name" :" text" ," _" :" Tween-20 in PBS PCCA" },{" #name" :" keyword" ," $" :{" id" :" kwrd0320" }," $$" :[{" #name" :" text" ," _" :" propionyl-CoA carboxylase alpha chain PD" },{" #name" :" keyword" ," $" :{" id" :" kwrd0330" }," $$" :[{" #name" :" text" ," _" :" pull down PDB" },{" #name" :" keyword" ," $" :{" id" :" kwrd0340" }," $$" :[{" #name" :" text" ," _" :" Protein Data Bank PDI" },{" #name" :" keyword" ," $" :{" id" :" kwrd0350" }," $$" :[{" #name" :" text" ," _" :" protein disulfide isomerase PLA" },{" #name" :" keyword" ," $" :{" id" :" kwrd0360" }," $$" :[{" #name" :" text" ," _" :" proximity ligation assay PPI" },{" #name" :" keyword" ," $" :{" id" :" kwrd0370" }," $$" :[{" #name" :" text" ," _" :" protein–protein interaction PYC" },{" #name" :" keyword" ," $" :{" id" :" kwrd0380" }," $$" :[{" #name" :" text" ," _" :" pyruvate carboxylase RT" },{" #name" :" keyword" ," $" :{" id" :" kwrd0390" }," $$" :[{" #name" :" text" ," _" :" room temperature RPN1" },{" #name" :" keyword" ," $" :{" id" :" kwrd0400" }," $$" :[{" #name" :" text" ," _" :" ribophorin 1 SILAC" },{" #name" :" keyword" ," $" :{" id" :" kwrd0410" }," $$" :[{" #name" :" text" ," _" :" stable isotope labeling with amino acids in cell culture THG" },{" #name" :" keyword" ," $" :{" id" :" kwrd0420" }," $$" :[{" #name" :" text" ," _" :" thapsigargin TUN" },{" #name" :" keyword" ," $" :{" id" :" kwrd0430" }," $$" :[{" #name" :" text" ," _" :" tunicamycin UT" },{" #name" :" keyword" ," $" :{" id" :" kwrd0440" }," $$" :[{" #name" :" text" ," _" :" urea–Tris
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