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Comparative Proteome Signatures of Trace Samples by Multiplexed Data-Independent Acquisition
Authors:Claudia Ctortecka  Gabriela Krššáková  Karel Stejskal  Josef M. Penninger  Sasha Mendjan  Karl Mechtler  Johannes Stadlmann
Affiliation:1. Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria;2. Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), Vienna, Austria;3. The Gregor Mendel Institute of Molecular Plant Biology of the Austrian Academy of Sciences (GMI), Vienna BioCenter (VBC), Vienna, Austria;4. Department of Medical Genetics, Life Sciences Institute, University of British Columbia, Vancouver Campus, Vancouver, British Columbia, Canada;5. Institute of Biochemistry, Department of Chemistry, University of Natural Resources and Life Sciences (BOKU), Vienna, Austria
Abstract:
Keywords:data-independent acquisition  isobaric multiplexing  large sample cohorts  identification-free data aggregation  ultralow peptide input  AGC"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0020"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  automatic gain control  DDA"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0020e"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  data-dependent acquisition  DIA"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0030"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  data-independent acquisition  NCE"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0040"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  normalized collision energy  PSM"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0050"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  peptide-to-spectrum match  RI"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0060"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  reporter ion  RT"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0070"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  retention time  TMT"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  kwrd0080"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  tandem-mass-tag
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