Assignment of the mouse desmin gene to chromosome 1 band C3 |
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Authors: | Z L Li M G Mattei J F Mattei D Paulin |
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Institution: | Laboratoire de Biologie Moléculaire de la Différenciation de l'Université Paris. |
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Abstract: | The chromosomal localization of the mouse gene coding for desmin, one of the muscle-specific intermediate filament subunits, was determined by in situ hybridization using a specific 3H-labelled DNA probe. There is only one copy of the desmin gene and it is located on chromosome 1 in the band C3. This result adds an eleventh locus to a conserved gene cluster and confirms the partial homology that exists between the long arm of human chromosome 2 and chromosome 1 of the mouse. |
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