| 大鼠出生后脑内钙调神经磷酸酶的研究 |
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| 引用本文： | 王健勇,曾菲菲,魏群. 大鼠出生后脑内钙调神经磷酸酶的研究[J]. 中国生物化学与分子生物学报, 1993, 9(1): 56-59 |
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| 作者姓名： | 王健勇 曾菲菲 魏群 |
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| 作者单位： | 北京师范大学分子生物学及生物化学研究室，北京师范大学分子生物学及生物化学研究室，北京师范大学分子生物学及生物化学研究室 北京 100875 1988届研究生，北京大学生化教研室，北京 100875 北京医科大学生化教研室，北京 100875 |
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| 摘 要： | 本文用BA-ELISA.immunoblotting及酶活力测定等方法,研究了大鼠脑中钙调神经磷酸酶在大鼠出生后的变化情况。结果表明,钙调神经磷酸酶的含量在大鼠出生后第二周和第三周显著增加,其活力也在出生后第二周达到顶峰。钙调神经磷酸酶这种有规律的变化与脑中突触形成在时间上是一致的,暗示钙调神经磷酸酶可能参与突触功能的调节。
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| 关 键 词： | 钙调神经磷酸酶 脑 发育 |
| 收稿时间： | 1993-02-20 |
Studies on Calcineurin of Rat Brains during their Development |
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| Wang,Jian-yong Zeng,Fei-fei. Studies on Calcineurin of Rat Brains during their Development[J]. Chinese Journal of Biochemistry and Molecular Biology, 1993, 9(1): 56-59 |
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| Authors: | Wang Jian-yong Zeng Fei-fei |
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| Affiliation: | (**) Wei, Qun (Depargment of Biochemistry, Beijing Normal University, Beijmg 100875 |
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| Abstract: | Using BA-ELISA immunoblotting and assay of enzyme activity, we studied the changes of calcineurin in rat brains during their development. The results indicate that the content of calcineurin increases significantly during the second and third week after birth. The activity of calcineurin reaches its peak during the second week after birth. The changes of calcineurin during the development of rat brains parallel with synaptogenesis, implicating that calcineurin involves the synaptic function. |
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| Keywords: | calcineurin brain development |
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