High-yield production and characterization of biologically active GST-tagged human topoisomerase IIα protein in insect cells for the development of a high-throughput assay期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

High-yield production and characterization of biologically active GST-tagged human topoisomerase IIα protein in insect cells for the development of a high-throughput assay

Authors:	Praveen K. Singh Pan F. Chan Martin J. Hibbs Maria-Jesus Vazquez Delfina C. Segura Daniel A. Thomas Andrew J. Theobald Kathleen T. Gallagher Namir J. Hassan

Affiliation:	^a Biological Reagents & Assay Development, GlaxoSmithKline R&D, New Frontiers Science Park, Third Avenue, Harlow, Essex, CM19 5AW, UK;^b Antibacterial Discovery Performance Unit, Infectious Diseases Centre of Excellence for Drug Discovery, GlaxoSmithKline R&D, 1250 South Collegeville Road, Collegeville, PA 19426, USA;^c Biological Reagents & Assay Development, GlaxoSmithKline R&D, Santiago Grisolía 4, 28760 Tres Cantos, Madrid, Spain;^d Molecular & Cellular Technologies, GlaxoSmithKline R&D, 1250 South Collegeville Road, Collegeville, PA 19426, USA

Abstract:

Keywords:	Yeast Topoisomerase ATPase DNA GST
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