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Resonance assignments of human C35 (C17orf37) protein, a novel tumor biomarker
Authors:Chun-Jiun Yang  Chi-Fon Chang  Lin-Ya Huang  Yu-Yung Chang  Tang-Long Shen  Chun-Hua Hsu
Affiliation:1. Genomics Research Center, Academia Sinica, Nankang, Taipei, 11529, Taiwan, ROC
2. Department of Plant Pathology and Microbiology, National Taiwan University, Taipei, 10617, Taiwan, ROC
3. Department of Agricultural Chemistry, National Taiwan University, Taipei, 10617, Taiwan, ROC
Abstract:A new tumor-specific target, termed C35 (C17orf37), has been identified by representational difference analysis of tumor and normal human mammary cell lines. C35 protein is considered to be an important target for cancer therapy, since the over expression of C35 functionally enhances migration and invasion of tumor cells. Here we report the NMR resonance assignments of C35 protein for further structural determination and functional studies.
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