Monoacylcadaverines in the blood of schizophrenic patients |
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Authors: | Hana Dolezalova Matej Stepita-Klauco Jan Kucera Hideyuki Uchimura Makoto Hirano |
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Affiliation: | Department of Biobehavioral Sciences, University of Connecticut, Storrs, Conn. 06268 U.S.A.;Department of Neurology, Washington University, St. Louis, Mo. 63110 U.S.A.;Hizen National Mental Hospital, Kanzaki, Saga 84201 Japan |
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Abstract: | Concentrations of cadaverine, monoacetylcadaverine and monopropionylcadaverine in the blood of schizophrenic and nonschizophrenic subjects were measured. Two groups, one from the U.S.A. the other from Japan, were tested. Monoacetylcadaverine and monopropionylcadaverine were found elevated in the blood of some schizophrenic patients in comparison with those in controls in each group. Their increase could be caused by a reduced monoamine oxidase activity or by an increased acylation in schizophrenic patients. |
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Keywords: | To whom correspondence should be addressed |
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