Predicted and experimental structures of integrins and beta-propellers |
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Authors: | Springer Timothy A |
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Affiliation: | Center for Blood Research and Department of Pathology, Harvard Medical School, Boston, Massachusetts 02115, USA. springeroffice@cbr.med.harvard.edu |
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Abstract: | Integrins and other cell surface receptors have been fertile grounds for structure prediction experiments. Recently determined structures show remarkable successes, especially with beta-propeller domain predictions, and also reveal how ligand binding by integrins is conformationally regulated. |
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