A model for thermal exchange in axons during action potential propagation |
| |
Authors: | J-B Masson G Gallot |
| |
Institution: | (1) Laboratoire d’Optique et Biosciences, Ecole Polytechnique, CNRS UMR 7645, INSERM U 696, 91128 Palaiseau, France;(2) Laboratoire de Genetique in Silico, Institut Pasteur, CNRS URA 2171, 25 rue du docteur Roux, 75724 Paris, France;(3) Laboratoire de Genetique des Genomes Bacteriens, Institut Pasteur, CNRS URA 2171, 28 rue du docteur Roux, 75724 Paris, France |
| |
Abstract: | Several experiments have shown that during propagation of the action potential in axons, thermal energy is locally exchanged.
In this paper, we use a simple model based on statistical physics to show that an important part of this exchange comes from
the physics of the effusion. We evaluate, during the action potential propagation, the variation of internal energy and of
the energy associated with the chemical potential of the effusion of water and ions to extract the thermal energy exchanged.
The temperature exchanged is then evaluated on the area where the action potential is active. Results give a good correspondence
between experimental work and this model, showing that an important part of the thermal energy exchange comes from the statistical
cooling power of the effusion. |
| |
Keywords: | Statistical physics Thermal analysis Neurons |
本文献已被 PubMed SpringerLink 等数据库收录! |
|