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An oligonucleotide microarray for detection and discrimination of orthopoxviruses based on oligonucleotide sequences of two viral genes |
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| Authors: | Riabinin V A Shundrin L A Kostina E V Laassri M Chizhikov V E Maksakova G A Baturina O A Pozdniakova L D Feshchenko M V Shchelkunov S N Chumakov K M Siniakov A N |
| Abstract: | An oligonucleotide microarray for detection and identification of orthopoxviruses was developed. Genus specific and orthopoxvirus species-specific regions of the genes encoding chemokine binding and alpha/beta-interferon binding proteins were used as a target. The developed microarray allows the variola, monkeypox, cowpox, vaccinia, camel-pox and ectromelia (mousepox) viruses to be distinguished with a high degree of reliability. |
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