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Specific Features of Repair DNA-Polymerases in Embryogenesis of the Loach
Authors:N P Sharova  E B Abramova  S B Dmitrieva  V S Mikhailov
Institution:(1) Russian Academy of Sciences, Kol'tsov Institute of Developmental Biology, ul. Vavilova 26, Moscow, 119991, Russia
Abstract:The current concept of eukaryotic DNA polymerases is considered, which are involved in nuclear DNA repair. The data are given on a new group of DNA polymerases that maintain the integrity of DNA structures without preliminary excision of damaged regions. A special attention is paid to specific features of the functioning of repair DNA polymerases in embryogenesis of the loach. A possible existence is discussed of the previously unknown pathway of DNA repair with participation of DNA polymerase delta as independent from the nuclear antigen of proliferating cells.
Keywords:DNA repair  DNA polymerases  embryogenesis of teleostean fish
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