| Abstract: | Given a family of related sequences, one can first determinealignments between various pairs of those sequences, then constructa simultaneous alignment of all the sequences that is determinedin a natural manner by the set of pairwise alignments. Thisapproach is sometimes effective for exposing the existence andlocations of conserved regions, which can then be aligned bymore sensitive multiple-alignment methods. This paper presentsan efficient algorithm for constructing a multiple alignmentfrom a set of pairwise alignments. |
