Deletion of Aldh4a1 Leads to Impaired Sperm Maturation in Mice |
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Authors: | Xiao Y. Wen Z. Z. Wu B. Zhu H. X. Zhang A. Z. Li J. Y. Gao J. G. |
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Affiliation: | 1.School of Life Science and Key Laboratory of the Ministry of Education for Experimental Teratology, Shandong University, 250100, Jinan, P.R. China ;2.Medical Science and Technology Innovation Center, Shandong First Medical University, 250117, Jinan, P.R. China ;3.Key Laboratory of Male Reproductive Health, Institute of Science and Technology, National Health Commission, 100081, Beijing, P.R. China ; |
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Abstract: | Molecular Biology - ALDH4A1, a member of the aldehyde dehydrogenase superfamily, is a key enzyme in the mitochondrial proline metabolism pathway. Recent studies have shown that mutations in aldh4a1... |
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