Syntheses of novel substituted-boranophosphate nucleosides |
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| Authors: | Vyakaranam Kamesh Rana Geeta Spielvogel Bernard F Maguire John A Hosmane Narayan S |
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| Institution: | Department of Chemistry and Biochemistry, Michael Faraday Laboratories, Northern Illinois University, DeKalb, IL 60115, USA. |
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| Abstract: | A number of substituted (borano) nucleic acids, 3'-diethylphosphite(cyano, carboxy, or carbamoyl) borano] deoxynucleosides (3a-4c) and 5'-diethylphosphite(cyano or carboxy) borano] deoxynucleosides (6a-7d) were prepared by a variety of synthetic procedures. The syntheses of the pyrophosphates (2a-2c), as precursors for 3a-4c, are also described. |
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