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Metronidazole in prevention and treatment of bacteroides infections in elective colonic surgery.
Authors:A T Willis  I R Ferguson  P H Jones  K D Phillips  P V Tearle  R V Fiddian  D F Graham  D H Harland  D F Hughes  D Knight  W M Mee  N Pashby  R L Rothwell-Jackson  A K Sachdeva  I Sutch  C Kilbey  D Edwards
Abstract:A double-blind randomised trial was carried out among 46 patients undergoing elective colonic surgery; 27 patients received prophylactic metronidazole and 19 received placebo. Anaerobic infections did not develop in any of the metronidazole-treated patients, but did develop in 11 (58%) of 19 controls who were subsequently successfully treated with metronidazole.
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