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| 蚯蚓提取物对小鼠肿瘤动物模型的研究 | |
| 引用本文： | 胡云龙,徐梅,张双全,黄文华,亢寿海,王俏先.蚯蚓提取物对小鼠肿瘤动物模型的研究[J].生物技术,2002,12(6):9-10. |
| 作者姓名： | 胡云龙 徐梅 张双全 黄文华 亢寿海 王俏先 |
| 作者单位： | 1. 南京师范大学生命科学院,江苏,南京210097 2. 中国药科大学,江苏,南京,210009 3. 上海国源生物技术公司,江苏,上海,200233 4. 江苏省肿瘤防治研究所,江苏,南京,210094 |
| 摘 要： | 目的 :研究蚯蚓提取物 (EFE)的免疫活性及抗肿瘤作用。方法 :采用小鼠移植性肿瘤S1 80 肉瘤及Heps肝癌的动物模型观察其肿瘤抑制作用。结果 :EFE对S1 80 肉瘤和Heps肝癌细胞的抑制率分别为 36 97%和 4 8 55% ;结论 :它对小鼠实体瘤细胞有明显的抑制作用 (P <0 0 1 )并提示对小鼠的细胞和体液免疫功能有显著增强作用。 |
| 关 键 词： | 蚯蚓提取物 小鼠 肿瘤 动物模型 抑制作用 |
| 文章编号： | 1004-311X(2002)06-0009-02 |
Study of earthworm extraction on the immunologic activity and antitumor effects |
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| HU Yun-Long,XU Mei,ZHANG Shuang-quan,HUANG Wen-Hua,KANG Shou-hai,WANG Qiao-Xian.Study of earthworm extraction on the immunologic activity and antitumor effects[J].Biotechnology,2002,12(6):9-10. | |
| Authors: | HU Yun-Long XU Mei ZHANG Shuang-quan HUANG Wen-Hua KANG Shou-hai WANG Qiao-Xian |
| Institution: | HU Yun-Long1,XU Mei4,ZHANG Shuang-quan1,HUANG Wen-Hua2,KANG Shou-hai3,WANG Qiao-Xian3 |
| Abstract: | Purpose:The aim was to study the immunologic activity and antitumor effects of earthworm extraction.Method:The antitumor effects and immunologic activity of earthworm extraction were observed by planting sarcoma180(S 180) and liver cancer(Heps-2) into bodies of mice or normal mice.Result:It has shown that the inhibiting rates of tumor were 36.97% and 48.55% respectively(P<0.01).Earthworm extraction obviously enhanced the function of phagocytosis of macrophage in abdominal cavity of mice.Conclusion:Earthworm extraction inhibited significantly the growth of tumor and enhanced the immunologic function. |
| Keywords: | earthworm extraction immunologic functoin anticancer |
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