Structure and evolution of the heavy chain from rat immunoglobulin E. |
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Authors: | L Hellman, U Pettersson, A Engstr m, T Karlsson, H Bennich |
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Affiliation: | L Hellman, U Pettersson, A Engström, T Karlsson, and H Bennich |
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Abstract: | The nucleotide sequence of the rat epsilon-chain mRNA has been determined by sequencing cloned cDNA copies of the mRNA. The established sequence covers the coding region, the 3'-non coding region and most of the 5' non-coding region. A comparison with the nucleotide sequence of the human epsilon-chain constant region reveals that C3 and C4 are the most highly conserved domains. The rat epsilon-chain contains a C-terminal decapeptide which is not present in the human counterpart. |
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