Bufadienolides from Drimia macrocentra and Urginea riparia (Hyacinthaceae: Urgineoideae) |
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| Authors: | Moodley Nivan Crouch Neil R Mulholland Dulcie A |
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| Institution: | School of Chemistry, University of KwaZulu-Natal, Howard College Campus, Durban 4041, South Africa. |
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| Abstract: | The bufadienolides, rubellin and riparianin were isolated from the bulbs of Drimia macrocentra and Urginea riparia (Hyacinthaceae) respectively. Rubellin and riparianin contain a carbohydrate moiety doubly linked to the bufadienolide aglycone at the C-2 and C-3 positions. Riparianin showed moderate activity when tested against MCF7 (breast), TK10 (renal) and UACC62 (melanoma) cell lines. |
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