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Identification of cyanobacterial non-coding RNAs by comparative genome analysis
Authors:Ilka?M?Axmann  Philip?Kensche  J?rg?Vogel  Stefan?Kohl  Hanspeter?Herzel  Email author" target="_blank">Wolfgang?R?HessEmail author
Institution:(1) Department of Biology/Genetics, Humboldt-University, Chausseestrasse, D-Berlin, Germany;(2) Institute for Theoretical Biology, Humboldt-University, Invalidenstrasse, Berlin, Germany;(3) Max Planck Institute for Infection Biology, Schumannstrasse, Berlin, Germany;(4) University Freiburg, Institute of Biology II/Experimental Bioinformatics, Schnzlestrasse, Freiburg, Germany
Abstract:

Background  

Whole genome sequencing of marine cyanobacteria has revealed an unprecedented degree of genomic variation and streamlining. With a size of 1.66 megabase-pairs, Prochlorococcus sp. MED4 has the most compact of these genomes and it is enigmatic how the few identified regulatory proteins efficiently sustain the lifestyle of an ecologically successful marine microorganism. Small non-coding RNAs (ncRNAs) control a plethora of processes in eukaryotes as well as in bacteria; however, systematic searches for ncRNAs are still lacking for most eubacterial phyla outside the enterobacteria.
Keywords:
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