TEAD1-dependent expression of the FoxO3a gene in mouse skeletal muscle |
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Authors: | Haifang Qiu Fengli Wang Chuxin Liu Xuewen Xu and Bang Liu |
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Institution: | (1) Key Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, Huazhong Agricultural University, 430070 Wuhan, China;(2) Weifang Bureau of Animal Husbandry, 261041 Weifang, China |
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Abstract: | Background
TEAD1 (TEA domain family member 1) is constitutively expressed in cardiac and skeletal muscles. It acts as a key molecule of muscle
development, and trans-activates multiple target genes involved in cell proliferation and differentiation pathways. However,
its target genes in skeletal muscles, regulatory mechanisms and networks are unknown. |
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Keywords: | |
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