DNA-interaction and in vitro antimicrobial studies of some mixed-ligand complexes of cobalt(II) with fluoroquinolone antibacterial agent ciprofloxacin and some neutral bidentate ligands |
| |
Authors: | M.N. Patel M.R. Chhasatia D.S. Gandhi |
| |
Affiliation: | Department of Chemistry, Sardar Patel University, Vallabh Vidyanagar, Gujarat 388 120, India |
| |
Abstract: | Six new mixed-ligand complexes of Co(II) with ciprofloxacin (Cip) and neutral bidentate ligands have been synthesized and characterized. Binding and cleavage of DNA with the complex were investigated using spectroscopic method, viscosity measurements and gel electrophoresis techniques. Antibacterial activity has been assayed against two Gram(?ve) and three Gram(+ve) microorganisms using the doubling dilution technique. |
| |
Keywords: | |
本文献已被 ScienceDirect 等数据库收录! |