Crown-capped imidacloprid: A novel design and insecticidal activity |
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| Authors: | Shinzo Kagabu Masaru Takagi Ikuya Ohno Tsuyoshi Mikawa Toru Miyamoto |
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| Institution: | 1. Department of Chemistry, Faculty of Education, Gifu University, Gifu 501-1193, Japan;2. Department of Applied Biology and Chemistry, Tokyo University of Agriculture, Tokyo 156-8502, Japan |
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| Abstract: | Imidacloprid (IMI) derivatives conjugated with benzo-15-crown-5 and benzo-18-crown-6 structures, applied for the first time to explore novel insecticidal molecule, elicited strong excitatory toxic signs to the house flies and stunningly exhibited three to five times higher insecticidal activity than that of the parent IMI, yet the two benzo-crown structures themselves had no effect. |
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