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Discovery of potent and selective DP1 receptor antagonists in the azaindole series |
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| Authors: | Yves Leblanc Patrick Roy Claude Dufresne Nicolas Lachance Zhaoyin Wang Gary O’Neill Gillian Greig Danielle Denis Marie-Claude Mathieu Deborah Slipetz Nicole Sawyer Nancy Tsou |
| Institution: | 1. Merck Frosst Centre for Therapeutic Research, PO Box 1005, Pointe Claire-Dorval, Quebec, Canada H9R 4P8;2. Merck Research Laboratories, PO Box 2000, Rahway, NJ 07065, USA |
| Abstract: | Azaindole based structures were evaluated as DP1 receptor antagonists. This work has lead to the discovery of potent, selective and distinct DP1 receptor antagonists. |
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