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Natural and experimental simian cytomegalovirus infections at a primate center
Authors:N S Swack  G D Hsiung
Abstract:Simian cytomegalovirus infections were studied in captive, naturally infected primates and in experimentally infected rhesus monkeys. Neutralizing antibody to simian cytomegalovirus was prevalent in selected species of Old World Monkeys. Naturally infected, rhesus monkeys shed virus in their urine during the entire two-year period of study. Similarly, experimentally infected rhesus monkeys showed neutralizing antibody and viruria for more than two years. The indirect fluorescent antibody procedure was found more sensitive than the neutralization antibody technique but appeared less specific for antibody to cytomegalovirus strains.
Keywords:Cytomegalovirus  African green monkey CMV  Simian CMV serology  CMV viruria  Experimental CMV infection  Rhesus monkeys
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