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丹红注射液治疗急性脑梗死的临床疗效分析
引用本文:樊文萍,黄学莲,马凤英,徐 萌,万齐华. 丹红注射液治疗急性脑梗死的临床疗效分析[J]. 现代生物医学进展, 2018, 0(9): 1772-1775
作者姓名:樊文萍  黄学莲  马凤英  徐 萌  万齐华
作者单位:青海省西宁市第一人民医院药品调配站;青海省西宁市第一人民医院心血管科;青海省西宁市第一人民医院风湿血液科;青海大学附属医院临床药学科;青海省西宁市第一人民医院临床药学科
基金项目:西宁市科技局立项项目(2014-k-08)
摘    要:目的:探讨丹红注射液治疗急性脑梗死的临床疗效。方法:选择2016年1月至2017年6月来我院进行治疗急性脑梗死疾病患者70例作为本研究的对象,采用随机数字表法均分为研究组和对照组。对照组采用常规抗血小板聚集、降低颅内压、营养脑细胞等治疗,研究组在对照组的基础上采用丹红注射液治疗,对比两组患者的疗效、治疗前后的神经功能缺损评分、日常生活活动能力评分、全血黏度和红细胞比积的变化。结果:治疗后,对照组患者的治疗有效率(82.86%)显著低于研究组(94.29%)(P0.05),研究组患者日常生活活动能力评分显著高于对照组(P0.05),神经功能缺损评分、全血黏度、红细胞比积均显著低于对照组(P0.05)。结论:丹红注射液用于治疗急性脑梗死可显著提高其临床疗效,明显提高患者日常生活能力,改善神经功能和血液流变学。

关 键 词:丹红注射液;急性脑梗死;神经功能缺损;临床疗效
收稿时间:2017-10-09
修稿时间:2017-10-30

Clinical Efficacy of Danhong Injection in the Treatment of Acute Cerebral Infarction
Abstract:ABSTRACT Objective: To investigate the clinical efficacy of danhong injection in the treatment of acute cerebral infarction. Methods: 70 cases of patients with acute cerebral infarction admitted in our hospital from January 2016 to June 2016 were selected as the research object and randomly divided into the research group and the control group with 35 cases in each group according to the digital random table method. The control group was given conventional treatment, including platelet aggregation and reduce intracranial pressure, nutri- tion brain cells, etc, while the research group was given danhong injection on the basis of control group, the curative effect, changes of nerve function defect grade, daily life activities ability score, whole blood viscosity and red blood cells were compared between two groups of patients before and after treatment. Results: After treatment, the treatment effective rate of control group was 82.86 %, which was significantly lower than that of the research group(94.29 %, P<0.05). The daily life activity score of research group was higher than that of the control group(P>0.05). while the neurological impairment score, blood viscosity and erythrocyte ratio were obviously lower than those of the control group(P<0.05). Conclusion: Danhong injection could remarkably enhance the clinical efficacy in the treatment of acute cerebral infarction, it could obviously enhance the daily living ability, improve the blood rheological index and nerve function.
Keywords:Danhong injection   Acute cerebral infarction   Neurologic defect   Clinical curative effect
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