音乐疗法对阿尔茨海默病患者的睡眠质量、生活质量、认知功能及激越行为的影响

目的:探讨音乐疗法对阿尔茨海默病(AD)患者睡眠质量、生活质量、认知功能及激越行为的影响。方法:选择2016年8月至2017年10月湖南省脑科医院收治的AD患者50例为研究对象,采用随机数字表法分为观察组和对照组各25例,对照组给予常规药物治疗及认知训练,观察组在对照组的基础上给予音乐疗法辅助治疗,于治疗前、治疗8周,治疗16周采用匹茨堡睡眠质量指数量表(PSQI)、睡眠状况自评量表(SRSS)、生活质量测定量表简表(WHOQOL-BREF)、简易智力状态检查量表(MMSE)、简明精神病评定量表(BPRS)和激越行为量表(CMAI)评价两组治疗效果。结果:两组治疗8周和治疗16周的PSQI评分、SRSS评分、BPRS评分、CMAI评分与治疗前比较均明显降低,且治疗16周与治疗8周比较进一步降低,观察组治疗8周和治疗16周的上述评分均低于对照组(P0.05);WHOQOL-BREF评分、MMSE评分治疗8周和治疗16周与治疗前比较明显提高,且治疗16周与治疗8周比较进一步提高,观察组治疗8周和治疗16周的上述评分均高于对照组(P0.05)。结论:音乐疗法辅助治疗AD可以进一步改善患者的睡眠质量、认知功能和激越行为,提高患者的生活质量。

Effect of Music Therapy on Sleep Quality, Life Quality, Cognitive Function and Agitation Behavior in Patients with Alzheimer Disease

ABSTRACT Objective: To explore the effect of music therapy on sleep quality, life quality, cognitive function and agitation behavior in patients with alzheimer disease(AD). Methods: 50 patients with AD were selected in Brain Hospital of Hunan Province as the subjects from August 2016 to October 2017, the patients were divided into observation group and control group accdrding to random number table method, 25 cases each group, the control group were treated with routine medication and cognitive training, the observation group were treated with music therapy assisted treatment on the basis of the control group, the effect between the two groups were judged by Pittsburgh sleep quality index (PSQI), self rating scale of sleep (SRSS), the determination of the quality of life scale (WHOQOL-BREF), Mini Mental State Examination (MMSE), the Brief Psychiatric Rating Scale (BPRS) and agitation scale (CMAI) at before treatment, 8 weeks after treatment and 16 weeks after treatment. Results: The PSQI scores, SRSS scores, BPRS scores and CMAI scores between the two groups at 8 weeks after treatment and 16 weeks after treatment were significantly lower than those at before treatment, and which were further decreased at 16 weeks after treatment compared with 8 weeks treatment, the scores in the observation group at 8 weeks after treatment and 16 weeks after treatment were lower than those in the control group (P<0.05). The WHOQOL-BREF score and MMSE score at 8 weeks after treatment and 16 weeks after treatment were significantly higher than those at before treatment, and which were further increased at 16 weeks after treatment compared with 8 weeks treatment, the scores in the observation group at 8 weeks after treatment and 16 weeks after treatment were higher than those in the control group(P<0.05). Conclusion: The music therapy in the treatment of Alzheimer disease can further improve the sleep quality, cognitive function and agitation behavior in patients, and can improve the life quality.