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每日2次和3次皮下注射诺和锐30疗效临床分析
引用本文:罗春英,李强翔,李晓春,王鸣鸿,吴建能. 每日2次和3次皮下注射诺和锐30疗效临床分析[J]. 现代生物医学进展, 2010, 10(6)
作者姓名:罗春英  李强翔  李晓春  王鸣鸿  吴建能
作者单位:1. 广东省粤北人民医院内分泌内科,广东,粤北,512026
2. 中南大学行政管理学院博士后流动站,湖南,长沙,410083
基金项目:湖南省博士后研究人员日常经费资助(2009年44号); 湖南省科技厅课题(2007FJ4135)
摘    要:
目的:比较诺和锐30每日2次和3次皮下注射的疗效和安全性。方法:为期3个月的随机、开放式试验,100例2型糖尿病(T2DM)患者随机分为诺和锐30皮下注射2次(每日早、晚餐前)、3次(早、中、晚餐前)组,观测两组患者空腹血糖(FPG),中餐前血糖,晚餐前血糖,睡前的血糖值以及糖化血红蛋白(HbA1c),低血糖事件及其他不良事件差异。结果:诺和锐30皮下注射3次组总体血糖水平低于2次组,低血糖事件和其他不良反应发生次数无显著性差异。结论:两组治疗方法均能有效地降低血糖,3次治疗组控制餐后血糖更具优势,HbA1c降低更好,未增加低血糖风险。

关 键 词:2型糖尿病  诺和锐30  皮下注射  

Subcutaneous Injection of Insulin Aspart 30: Comparison of 2 and 3 Times Daily
LUO Chun-ying,LI Qiang-xiang,LI Xiao-chun,WANG Ming-hong,WU Jian-neng. Subcutaneous Injection of Insulin Aspart 30: Comparison of 2 and 3 Times Daily[J]. Progress in Modern Biomedicine, 2010, 10(6)
Authors:LUO Chun-ying  LI Qiang-xiang  LI Xiao-chun  WANG Ming-hong  WU Jian-neng
Affiliation:LUO Chun-ying,LI Qiang-xiang,LI Xiao-chun,WANG Ming-hong,WU Jian-neng (The YueBei Hospital,Shaoguan,Guangdong 512026,China)
Abstract:
Objective: To compare the efficacy and safety of the Insulin Aspart 30 Injection inject 2 times and 3 times each day.Methods: The period of 3 months trials,100 T2DM patients were randomly divided into 2 times (before breakfast and dinner)and 3 times (before breakfast,lunch and dinner) group,observed the differences of the blood sugar between two groups of patients with before meals,before going to bed,as well as HbA1c,and other differences in adverse events.Results: The group of 3 times has a lower result t...
Keywords:T2DM  aspart 30  subcutaneous injection  
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