5-lipoxygenase: regulation and possible involvement in atherosclerosis |
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Authors: | Rådmark Olof Samuelsson Bengt |
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Affiliation: | Department of Medical Biochemistry and Biophysics, Division of Physiological Chemistry II, Karolinska Institute, S-17177 Stockholm, Sweden. olof.radmark@ki.se |
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Abstract: | This review article focuses on two aspects regarding 5-lipoxygenase. First, mechanisms for activation of the enzyme. Second, the involvement of 5-lipoxygenase and leukotrienes in atherosclerosis. |
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