Evidence for a heritable predisposition to Chronic Fatigue Syndrome |
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Authors: | Frederick Albright Kathleen Light Alan Light Lucinda Bateman and Lisa A Cannon-Albright |
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Institution: | (1) Pharmacotherapy Outcomes Research Center, Department of Pharmacotherapy, College of Pharmacy, University of Utah, Salt Lake City, Utah, USA;(2) Department of Anaesthesiology, University of Utah, Salt Lake City, Utah, USA;(3) Fatigue Consultation Clinic, Salt Lake City, UT, USA;(4) Division of Genetic Epidemiology, Department of Internal Medicine, School of Medicine, University of Utah, Salt Lake City, Utah, USA;(5) George E. Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, Utah, USA |
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Abstract: | Background Chronic Fatigue Syndrome (CFS) came to attention in the 1980s, but initial investigations did not find organic causes. Now
decades later, the etiology of CFS has yet to be understood, and the role of genetic predisposition in CFS remains controversial.
Recent reports of CFS association with the retrovirus xenotropic murine leukemic virus-related virus (XMRV) or other murine
leukemia related retroviruses (MLV) might also suggest underlying genetic implications within the host immune system. |
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