Transient integral boundary layer method to calculate the translesional pressure drop and the fractional flow reserve in myocardial bridges |
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Authors: | Stefan Bernhard Stefan Möhlenkamp Andreas Tilgner |
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Institution: | 1. Department of Physics, Georg-August-Universit?t G?ttingen, Friedrich-Hundt-Platz 1, 37077, G?ttingen, Germany 2. University Clinic of Essen, West-German Heart Center, Clinic of Cardiology, Hufelandstrasse 55, 45122, Essen, Germany
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Abstract: | Background The pressure drop - flow relations in myocardial bridges and the assessment of vascular heart disease via fractional flow
reserve (FFR) have motivated many researchers the last decades. The aim of this study is to simulate several clinical conditions
present in myocardial bridges to determine the flow reserve and consequently the clinical relevance of the disease. From a
fluid mechanical point of view the pathophysiological situation in myocardial bridges involves fluid flow in a time dependent
flow geometry, caused by contracting cardiac muscles overlying an intramural segment of the coronary artery. These flows mostly
involve flow separation and secondary motions, which are difficult to calculate and analyse. |
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