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Specificity of the rat hepatocyte monosaccharide transporter
Authors:K R Elliott  A J Bate  J D Craik
Affiliation:1. Department of Psychology, Stanford University, Stanford, CA, USA;2. School of Psychological Science, Oregon State University, Corvallis, OR, USA;3. Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA;4. Department of Psychology, Sungshin University, Seoul, South Korea;1. Aix-Marseille University and CNRS, Laboratoire de Psychologie Cognitive (UMR 7290), Fédération de recherche 3C, Marseille, France;2. Department of Public Policies and Collective Health, Federal University of São Paulo, Santos, Brazil;3. Aix Marseille University and CNRS, Laboratoire Parole et Langage (UMR 6057), 13 100, Aix-en-Provence, France;1. Laboratory of Ethology and Animal Welfare (LEBA), Department of Veterinary Medicine, University of Perugia, Via San Costanzo 4, 00126, Perugia, Italy;2. Istituto Zooprofilattico Sperimentale dell''Umbria e delle Marche “Togo Rosati”, Via Salvemini 5, 06126, Perugia, Italy;3. Public Veterinary Services for Urban Hygiene and Prevention of Stray Dogs, USL Umbria 1, Municipal Rescue Dog Shelter, Strada per Brufa snc, 06148, Collestrada, Perugia, Italy
Abstract:The effect of a number of hexoses and pentoses on 3-O-methyl-D-glucose transport into isolated hepatocytes is reported. The hexoses tested inhibited transport in a competitive manner, with Ki values ranging from 80 to 190 mM. No significant inhibition was seen with either D-ribose or D-arabinose.
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