Compositional changes of human mitral valves with aging |
| |
Authors: | Tohno Yoshiyuki Tohno Setsuko Satoh Hiroyasu Minami Takeshi Moriwake Yumi Azuma Cho Ohnishi Yoshiaki |
| |
Institution: | (1) Laboratory of Cell Biology, Department of Anatomy, Nara Medical University, Kashihara, 634-8521 Nara, Japan;(2) Department of Pharmacology, Nara Medical University, Kashihara, 634-8521 Nara, Japan;(3) Kinki University Toyo-oka Junior College, Toyo-oka, 668-8580 Hyogo, Japan |
| |
Abstract: | To elucidate compositional changes of the mitral valve with aging, the authors investigated the relationships among element
contents in the mitral valves. The subjects consisted of 10 men and 15 women, ranging in age from 65 to 102 yr. After the
ordinary dissection, mitral valves, lower parts of the interventricular septa, and terminal crests containing the sinoatrial
nodes were resected and the element contents were determined by inductively coupled plasma-atomic emission spectrometry. The
interventricular septa and sinoatrial nodes were used to compare with the mitral valves. With regard to the mitral valve,
it was found that extremely significant correlations were found among the contents of Ca, P, Mg, and Na, but no significant
correlations were found between the contents of S and elements such as Ca, P, or Mg. Regarding the interventricular septum,
it was found that an extremely significant correlation was found between P and S contents; very significant correlations were
found between Ca and Mg contents and between Mg and S contents; and a significant correlation was found between P and Mg contents.
However, no significant correlation was found between Ca and P contents in the interventricular septa. In the terminal crest
containing the sinoatrial node, significant correlations were found among the contents of Ca, P, Mg, and S. The present study
revealed that with regard to the relationships among element contents, the compositional change of the mitral valve was intermediate
between those of the thoracic aorta and the interventricular septum. |
| |
Keywords: | Mitral valve interventricular septum sinoatrial node calcium phosphorus magnesium aging |
本文献已被 PubMed SpringerLink 等数据库收录! |
|