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Neuropeptide Y Gene Polymorphisms Confer Risk of Early-Onset Atherosclerosis
Authors:Svati H. Shah   Neil J. Freedman   Lisheng Zhang   David R. Crosslin   David H. Stone   Carol Haynes   Jessica Johnson   Sarah Nelson   Liyong Wang   Jessica J. Connelly   Michael Muehlbauer   Geoffrey S. Ginsburg   David C. Crossman   Christopher J. H. Jones   Jeffery Vance   Michael H. Sketch   Jr   Christopher B. Granger   Christopher B. Newgard   Simon G. Gregory   Pascal J. Goldschmidt-Clermont   William E. Kraus     Elizabeth R. Hauser
Abstract:Neuropeptide Y (NPY) is a strong candidate gene for coronary artery disease (CAD). We have previously identified genetic linkage to familial CAD in the genomic region of NPY. We performed follow-up genetic, biostatistical, and functional analysis of NPY in early-onset CAD. In familial CAD (GENECARD, N
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