Establishment of postal audit system in intensity-modulated radiotherapy by radiophotoluminescent glass dosimeters and a radiochromic film |
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| Institution: | 1. Department of Radiation Oncology, National Cancer Center Hospital, 104-0045 Tokyo, Japan;2. Center for Cancer Control and Information Services, National Cancer Center, Tokyo 104-0045, Japan;3. Division of Medical Physics, Department of Information Technology and Medical Engineering, Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto 606-8507, Japan;4. Department of Radiation Measurement and Dose Assessment, National Institute of Radiological Sciences (NIRS), National Institutes for Quantum and Radiological Science and Technology (QST), Chiba 263-8555, Japan;5. Division of Medical Physics, Tokyo Bay Advanced Imaging & Radiation Oncology Makuhari Clinic, Chiba 261-0024, Japan;6. Department of Medical Physics, Graduate School of Medicine, Tokyo Women''s Medical University, Tokyo 162-8666, Japan;7. Department of Radiation Oncology, Kindai University Faculty of Medicine, Osaka 589-8511, Japan;1. Department of Radiation Convergence Engineering, College of Health Science, Yonsei University, 1 Yonseidae-gil, Wonju, Gangwon 220-710, Republic of Korea;2. Department of Radiological Science, College of Health Science, Yonsei University, 1 Yonseidae-gil, Wonju, Gangwon 220-710, Republic of Korea;1. Doctoral Program in Medical Physics, Graduate School of Medicine, Tokyo Women’s Medical University, Tokyo 1628666, Japan;2. Particle Therapy Division, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Chiba 2778577, Japan;3. Doctoral Program in Biomedical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Chiba 3058577, Japan;1. Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami Ward, Hiroshima 734-8551, Japan;2. Department of Radiation Oncology, Institute of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami Ward, Hiroshima 734-8551, Japan;3. Hiroshima High-Precision Radiotherapy Cancer Center, 3-2-2 Futabanosato, Higashi-ku, Hiroshima 732-0057, Japan;4. Section of Radiation Therapy, Department of Clinical Support, Hiroshima University Hospital, 1-2-3 Kasumi, Minami Ward, Hiroshima 734-8551, Japan;1. Department of Radiation Oncology, National Cancer Center Hospital, Tokyo, Japan;2. Department of Radiation Oncology, Instituto Nanional del Cancer, Santiago, Chile;3. Department of Gynecology, National Cancer Center Hospital, Tokyo, Japan;4. Department of Radiology, Okinawa Chubu Hospital, Okinawa, Japan;1. Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto 606-8507, Japan;2. Division of Medical Physics, Department of Information Technology and Medical Engineering, Human Health Sciences, Graduate School of Medicine, Kyoto University, 53 Kawahara-cho, Shogoin, Sakyo-ku, Kyoto, 606-8507, Japan |
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| Abstract: | We developed an efficient postal audit system to independently assess the delivered dose using radiophotoluminescent glass dosimeters (RPLDs) and the positional differences of fields using EBT3 film at the axial plane for intensity-modulated radiotherapy (IMRT). The audit phantom had a C-shaped target structure as a planning target volume (PTV) with four measurement points for the RPLDs and a cylindrical structure as the organ at risk (OAR) for one measurement point. The phantoms were sent to 24 institutions. Point dose measurements with a 0.6 cm3 PTW farmer chamber were also performed to justify glass dosimetry in IMRT. The measured dose with the RPLDs was compared to the calculated dose in the institution’s treatment planning system (TPS). The mean ± 1.96σ of the ratio of the measured dose with the RPLDs to the farmer chamber was 0.997 ± 0.024 with no significant difference (p = .175). The investigations demonstrated that glass dosimetry was reliable with a high measurement accuracy comparable to the chamber. The mean ± 1.96σ for the dose differences with a reference of the TPS dose for the PTV and the OAR was 0.1 ± 2.5% and ?2.1 ± 17.8%, respectively. The mean ± 1.96σ for the right-left and the anterior–posterior direction was ?0.9 ± 2.8 and 0.5 ± 1.4 mm, respectively. This study is the first report to justify glass dosimetry for implementation in IMRT audit in Japan. We demonstrate that our postal audit system has high accuracy with a high-level criterion of 3%/3 mm. |
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| Keywords: | Audit Radiophotoluminescent glass dosimeter Radiochromic film IMRT QA/QC |
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