Geant4 implementation of inter-atomic interference effect in small-angle coherent X-ray scattering for materials of medical interest |
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| Affiliation: | 1. INFN – Sez. Ferrara, Via G. Saragat 1, 44122 Ferrara, Italy;2. Dipartimento di Fisica e Scienze della Terra, Università di Ferrara, Via G. Saragat 1, 44122 Ferrara, Italy;1. Horia Hulubei National Institute for Physics and Nuclear Engineering, Reactorului 30, 077125 Bucharest-Măgurele, Romania;2. University of Bucharest, Faculty of Physics, Atomistilor 405, 077125 Bucharest-Măgurele, Romania;3. Horia Hulubei National Institute for Physics and Nuclear Engineering, ELI-NP, Reactorului 30, 077125 Bucharest-Măgurele, Romania;1. Department of Medical Physics and Biomedical Engineering, Sahlgrenska University Hospital, Gothenburg, Sweden;2. Department of Radiation Physics, Sahlgrenska Academy at the University of Gothenburg, Sweden;3. Department of Radiation Physics, Skåne University Hospital, Lund, Sweden;4. Department of Oncology, University of Gothenburg, Sweden;1. Medical Physics Service, Hospital Clínico San Carlos and IdISSC, 28040 Madrid, Spain;2. Radiology Department, Medicine Faculty, Universidad Complutense de Madrid, 28040 Madrid, Spain;3. Philips Healthcare, Best, The Netherlands;1. Department of Basic and Applied Sciences, Punjabi University, Patiala 147002, India;2. Nuclear Physics Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400 085, India;3. Inter University Accelerator Center, Aruna Asaf Ali Marg, New Delhi 110067, India |
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| Abstract: | An extension to Geant4 Monte Carlo code was developed to take into account inter-atomic (molecular) interference effects in X-ray coherent scattering. Based on our previous works, the developed code introduces a set of form factors including interference effects for a selected variety of amorphous materials useful for medical applications, namely various tissues and plastics used to build phantoms. The code is easily upgradable in order to include new materials and offers the possibility to model a generic tissue as a combination of a set of four basic components. A dedicated Geant4 application for the simulation of X-ray diffraction experiments was created to validate the proposed upgrade of Rayleigh scattering model. A preliminary validation of the code obtained through a comparison with EGS4 and an experiment is presented, showing a satisfactory agreement. |
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| Keywords: | Coherent scattering SAXS Molecular interference Monte Carlo simulations Geant4 |
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