An immunohistochemical study of somatostatin in the ovine, porcine and rodent pineal gland

Using anti-somatostatin in an immunoperoxidase technique at the light microscope level, somatostatin-like immunoreactivity was detected in ovine, porcine and rodent pineal glands. Positively stained cell bodies of various sizes and cellular processes were found throughout the glands. The chemical identity of this immunoreactive material and its physiologic significance remain to be determined.