Bactericidal activity of different oxovanadium(IV) complexes with Schiff bases and application of chelation theory |
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Authors: | Panchal Pragnesh K Parekh Hitesh M Pansuriya Pramod B Patel Mohan N |
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Affiliation: | Department of Chemistry, Sardar Patel University, Vallabh Vidyanagar-388 120, Gujarat, India. |
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Abstract: | Oxovanadium(IV) complexes have been synthesized and characterized the general composition [VOL(A)], where H2L = salicylidene-o-aminothiophenol A1 = bis(benzylidene)ethylenediamine, A2 = bis(acetophenone)ethylenediamine, A3 = 2,2'-bipyridylamine, A4 = bis(benzylidene) - 1,8-diaminonaphthalene, A5 = thiophene-o-carboxaldeneaniline and A6 = thiophene-o-carboxaldene-p-anisidine. Spectral studies indicate that the oxovanadium(IV) complexes assume a six-coordinate octahedral geometry. The antibacterial activities of the complexes against Salmonella typhi, Escherichia coli and Serratia mercescens are higher as compared to the free ligands, vanadyl sulphate, and the control (DMSO) but of moderate activity as compared to the standard drug (tetracycline). |
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