Synthesis and antimicrobial activity of some novel phenyl and benzimidazole substituted benzyl ethers |
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| Authors: | Güven Ozden Ozel Erdoğan Taner Göker Hakan Yildiz Sulhiye |
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| Affiliation: | Department of Chemistry, Zonguldak Karaelmas University, 67100 Zonguldak, Turkey. ozdenozel_guven@yahoo.com |
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| Abstract: | In this study, a series of novel phenyl- and benzimidazole-substituted benzyl ethers were synthesized and evaluated for antibacterial and antifungal activities against Staphylococcus aureus, Methicillin-resistant S. aureus (MRSA), Escherichia coli, Candida albicans, and Candida krusei. Compound 6g exhibited the most potent antibacterial activity with lowest MIC values of 3.12 and 6.25 microg/mL against S. aureus and MRSA, respectively. |
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