Fluorescent amplified-fragment length polymorphism analysis of the MRSA epidemic |
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| Authors: | Grady R O'Neill G Cookson B Stanley J |
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| Affiliation: | Molecular Biology Unit, Central Public Health Laboratory, London, UK. |
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| Abstract: | Genotypes and putative genetic relationships were characterised for epidemic methicillin-resistant Staphylococcus aureus (EMRSA) strains and isolates from England and Wales, using a high resolution DNA fingerprinting technique, fluorescent amplified-fragment length polymorphism (FAFLP). Each of the phage types of EMRSA had a distinct FAFLP profile. The technique revealed clusters of strains and isolates, and could distinguish isolates belonging to the same phage type. FAFLP provides a new approach to the epidemiological study and control of MRSA. |
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| Keywords: | Fluorescent amplified-fragment length polymorphism Methicillin-resistant Staphylococcus aureus |
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