Use of Old World monkeys for acquired immunodeficiency syndrome research |
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| Authors: | I Nicol D Messinger P Dubouch J Bernard I Desportes R Jouffre R Snart P Nara R C Gallo D Zagury |
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| Affiliation: | Laboratoire de Physiologie Cellulaire, Université Pierre et Marie Curie, Paris, France. |
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| Abstract: | Mangabeys, macaques, and baboons persistently infected with human immunodeficiency virus (HIV)-2 NIH-DZ demonstrated no signs of immunodeficiency disease after 6-11 months following seroconversion. Thus Old World monkeys provide an animal model to investigate the effects of passive immunization (anti-HIV-2 antibodies) on HIV infection in primates. |
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| Keywords: | Coculture Antibodies ELISA EM HIV-2 Monkeys |
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