Behavioural mode of action of deet: inhibition of lactic acid attraction |
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Authors: | Dogan E B Ayres J W Rossignol P A |
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Affiliation: | Department of Entomology and;College of Pharmacy, Oregon State University, Corvallis, U.S.A. |
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Abstract: | Using the mosquito Aedes aegypti in a novel olfactometer that measures movement towards and away from a stimulus, we could not confirm that 'deet' is a repellent of mosquitoes. In the absence of a host, deet was an attractant and in the presence of a host, it was an inhibitor of attraction. This inhibition occurred in the gaseous phase and was therefore not the result of the physical properties of deet. We determined that L-lactic acid, a component of human sweat that is an attractant to mosquitoes, is the target of this inhibition, implying that lactic acid may be a bottleneck in the behavioural cascade preceding blood-sucking. |
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Keywords: | Aedes aegypti deet lactic acid olfactometer attraction inhibition mosquito repellent |
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